Psoriasis Research Today is a free monthly online journal that collates and summarizes the latest research about Psoriasis, including details on treatment, prevention, medication, causes.

Acitretin induces capillary leak syndrome in a patient with pustular psoriasis.

Vos LE, Vermeer MH, Pavel S

Department of Dermatology, Leiden University Medical Center, The Netherlands. l.e.vos@lumc.nl

Capillary leak syndrome is a rare and potentially life-threatening condition caused by a shift of intravascular fluid and proteins to the interstitial space. We describe a patient with pustular psoriasis in whom capillary leak syndrome developed after the start of acitretin. Immediate withdrawal of retinoic acid is necessary and corticosteroid therapy should be considered.

Published 16 January 2007 in J Am Acad Dermatol, 56(2): 339-42.
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